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Kisspeptin and the GnRH pulse disorder The LH hypersecretion characteristic of PCOS originates in the hypothalamus, where an abnormally rapid GnRH pulse frequency drives excess LH production while suppressing FSH relatively

Diarrhea Diarrhea might seem contradictory given the constipation discussion, but GI motility disruption can manifest in either direction depending on the individual

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Understanding this helps me optimize treatment protocols

doi: 10.1038/138032a0

Regul Pept 181:5066 Boban Blagaic A, Blagaic V, Mirt M et al (2005) Gastric pentadecapeptide BPC 157 effective against serotonin syndrome in rats